Red Grape Skin Extract

(Vitis vinifera)

DRI (RDA or AI for Adults)

None

Adult Maintenance - Therapeutic Range

200 - 1,000 mg (@30% anthocyanins)

Major Sources

Red grape skins

Non-Therapeutic Importance

None

Possible Therapeutic Applications

CONSULT WITH A HEALTH PROFESSIONAL FIRST: Red Grape Skin extract contains a mix of substances, some of which are found in grape seeds and some in red wine. These substances include nonbioflavonoid polyphenols (derivatives of cinnamic and benzoic acid) and bioflavonoid polyphenols (quercetin, catechins, flavonols, and anthocyanidins). One of these ingredients, resveratrol, was found to have antiplatelet aggregating activity. Red wine has gotten a lot of press recently, sometimes being called the "French Paradox." The reason for this is that, while Frenchmen have a high-fat diet, they have one-third as many heart attacks as American men, although they have similar high cholesterol and blood pressure levels as their American counterparts. The main reason for this effect may be the polyphenols (OPCs; see also Grape Seed Extract) from the grape skin, not the alcohol content of the wine. Supplementation may prevent, or be helpful with, the following conditions:

Aging
Atherosclerosis (heart disease)
Capillary Fragility (bruising)
Diabetes
Inflammation (including bursitis)
Macular Degeneration
Raynaud's Disease
Varicose Veins
Wound Healing