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Nutrient Introduction
 

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WHY TAKE NUTRITIONAL SUPPLEMENTS?

People take supplements for five main reasons:

  1. To avoid basic nutrient deficiencies, mostly because of less-than-perfect eating habits.
  2. To treat current health problems.
  3. To prevent health problems, especially when there is a genetic predisposition or an increased environmental risk. (Cancer, heart disease, and osteoporosis are good examples.)
  4. To achieve optimal health.
  5. To delay and reduce the effects of aging.

Reason #1
Many government and independent food surveys show that the average American diet is deficient in anywhere from a couple to a half dozen or more important nutrients. These deficiencies include the much discussed antioxidants. Basic nutritional formulas can usually satisfy these fundamental nutritional inadequacies. However, for the following reasons #2 through #5, a wider range of nutrients, at higher potencies, is required.

Reason #2
There is no question now that higher than Recommended Dietary Allowance (RDA) levels of nutrients can help in the treatment of many ailments. When given half a chance, the human body can usually take care of itself. That means giving it the nutrients it needs, along with avoiding antinutrients (especially nicotine, caffeine, and alcohol).

Many health practitioners now use high doses of vitamins, minerals, essential fatty acids, coenzymes, and phytochemicals to treat diseases. The use of these nutrients often has few negative side effects and, unlike most pharmaceutical medications, has many positive side effects.

Reason #3
One of the best uses of nutritional supplements is in the prevention of disease. For instance, even the National Institutes of Health (NIH) has reported that about two-thirds of all cancers are diet and environment related. Simply put, if you have plenty of the right nutrients in your diet (especially antioxidants), while avoiding the cancer-causing chemicals found in food (nitrosamines, aflatoxins, etc.), you can reduce your chances of getting a diet-related cancer. Our environment presents cancer-causing hazards in the forms of air and water pollution. And here too, nutrients can help—namely the antioxidants.

Another good example in disease prevention is heart disease. Atherosclerosis is the form of heart disease by which the coronary arteries become blocked with cholesterol deposits, often resulting in a heart attack (myocardial infarction). While low-density lipoprotein cholesterol (LDL-C) is implicated in this process, it may not be the main initiator. The leading theory of heart disease now considers this substance hazardous only when it becomes oxidized (ox-LDL-C). That is because LDL-cholesterol is not only natural, you actually cannot live without it! To prevent LDL-C from oxidizing (essentially becoming rancid), you need to consume mostly monounsaturated fatty acids (olive and canola oils) and a full range of antioxidants. Another theory of heart disease (originally proposed by Dr. Kilmer McCully more than 25 years ago) considers homocysteine, a byproduct of a high animal protein diet, a culprit in causing atherosclerosis. To prevent this problem, an adequate intake of vitamin B6, vitamin B12, and folic acid, is needed.

Finally, osteoporosis is the classic example of a disease that is preventable with a proper nutrient intake and a supportive lifestyle. Unfortunately, calcium has been oversold as the answer to osteoporosis. While calcium is indeed important, you need a whole panoply of nutrients, including vitamins (B6, B12, folic acid, C, D, and K), and minerals (boron, copper, magnesium, manganese, and zinc). Other important factors in preventing and treating osteoporosis include moderate (not high) intakes of protein and phosphorous, reducing or avoiding nicotine, caffeine, and alcohol, and an appropriate aerobic and anaerobic exercise program.

Reason #4
Optimal health means more than the absence of disease—it means high-level wellness. This is where you have the energy and desire to do whatever needs to be done in your life, without relying on artificial stimulants. There are four essential components for high-level wellness: (1) a good, well-balanced diet; (2) a proper nutritional supplement program; (3) regular exercise; and (4) a positive mental attitude.

In the above context, nutritional supplementation means at levels above the RDA. The RDAs are not necessarily optimal levels, and to quote the 10th Edition of the National Research Council’s Recommended Dietary Allowances, the RDAs ". . . are judged by the Food and Nutrition Board to be adequate to meet the known nutrient needs of practically all healthy persons." [Italics added for emphasis.] The use of the words ‘adequate,’ ‘known,’ ‘practically,’ and ‘healthy,’ does not engender any confidence in the RDAs being optimal for everyone, especially for those unlucky people who are not healthy. Also, the RDAs are based on the absence of clinical signs of disease, not the presence of optimal health. There is a big difference between not being overtly sick, and being vibrantly healthy.

Reason #5
These days, people are living longer. However, that does not mean they are living better. In the wild, animals that avoid predation and accidents are usually healthy until they near their maximum potential lifespan. They then experience multi-organ failure and die. Humans, on the other hand, because of their ‘civilized diets’ of undernutrition and overconsumption, start their decline in their thirties and forties, even though our potential lifespan is around 120 years.

There are many theories of aging, including (1) errors in protein synthesis, turnover, and cross-linkage; (2) DNA damage; (3) organ system-pacemaker theory; (4) calorie overconsumption; and (5) free radical damage. Nevertheless, whatever theory (or theories) may be the right one, nutrition will play an important role. That is because one leading theory of aging (free radical damage) we have an easy answer to—a full and balanced intake of antioxidants.

 

THE ANTIOXIDANT CHAIN

A balanced intake of antioxidants is an important point to consider. That is because when an antioxidant neutralizes a free radical, the antioxidant itself becomes oxidized and can act as a free radical. In the body, more than a dozen molecules have antioxidant properties. Often one antioxidant may interact with one or more other antioxidant molecules. A good example is the relationship between vitamin E, vitamin C, glutathione, and glutathione reductase. When vitamin E neutralizes (reduces) a free radical and becomes oxidized, vitamin C neutralizes it. Then vitamin C becomes oxidized and glutathione reduces it, becoming oxidized in turn. Finally, the enzyme glutathione reductase neutralizes the oxidized glutathione. This is a balanced and complete antioxidant chain.

When there is an overconsumption of one antioxidant (e.g., beta-carotene or vitamin C), an unbalanced or incomplete antioxidant chain is created. This actually adds to the body’s free radical burden and possibly reduces the effectiveness of other antioxidants. As with many things in life, moderation and balance are the best way to go.

 

BEYOND VITAMINS AND MINERALS

The basic vitamins and minerals are as important as ever, but in the last twenty years or so, other nutrients have stolen the spotlight. These nutrients include:

Fish (cold water) and Plant Oils (black currant, borage, and evening primrose)
They supply the essential fatty acids omega-3 (EPA/DHA) and omega-6 (GLA), respectively. These oils are precursors for prostaglandins, hormone-like molecules. While these essential oils can help many ailments, they are particularly beneficial for the cardiovascular and immune systems.

Coenzyme Q10
Found in almost every living cell on the planet, this coenzyme (sometimes called ubiquinone because it is ubiquitous) has been researched since the 1950s. CoQ10 is a vital link in the Electron Transport Chain, a pathway in the body that results in the production of ATP (adenosine triphosphate), a molecule often called the energy currency of the body. While our bodies manufacture it, supplementation can be very beneficial, especially with people over the age of thirty. CoQ10 is most helpful in treating ailments affecting the cardiovascular and immune systems.

Plant Polyphenols
There are thousands of these bioactive substances, found in plants, including fruits and vegetables. Some of the more researched and clinically proven ones include:

  • BILBERRY: Well-known for its beneficial effects on vision, bilberry is useful in many other areas, too.
  • GINKGO BILOBA: The ginkgo tree has been around for several hundred million years. Obtained from its leaves, ginkgo extract is most recognized for its valuable effects on the brain. Hundreds of scientific papers have been published attesting to its memory-enhancing attributes. Ginkgo extract has many other clinical applications, also.
  • GRAPE SEED: Classified as an OPC (oligomer proanthocyanidin), grape seed extract is very similar to Pycnogenol® in form and function. It helps with inflammation, bruising, wound healing, and heart disease. It is also a good antioxidant.
  • GRAPE SKIN: Related to grape seed extract and Pycnogenol®, flavonoids in grape skins are also beneficial in preventing heart disease, as well as having other attributes.
  • GREEN TEA: Made from green tea, it is noted for its anticancer properties. It has also been shown to be helpful for the cardiovascular and immune systems.
  • LEMON/CITRUS BIOFLAVONOIDS: Often derived from the inner rind of lemons, these bioflavonoids are helpful throughout the body.
  • MILK THISTLE: Commonly called silymarin, research shows that it exhibits liver-protective qualities. In addition, silymarin is helpful for the cardiovascular and immune systems.
  • POMEGRANATE: Extracts from this exotic fruit contain the polyphenols, anthocyanosides and punicosides (punicalagin, ellagic acid, delphinidin, pelargonidin, and cyanidin), which may help with heart disease, cancer, high blood pressure, and osteoarthritis.
  • QUERCETIN: A water-soluble plant pigment (flavonoid) that is found in apples, berries, green and black tea, onions, and red wine. It has antioxidant and anti-inflammatory properties. It helps with allergies, and reduces diabetic complications.
  • TURMERIC: The curcuminoids found in turmeric have a number of properties, including anti-inflammatory and antioxidant.

Ginger
Helpful for nausea and motion sickness, ginger also improves digestion and nutrient absorption.

Lipoic Acid
Found in two Krebs cycle enzymes, lipoic acid is critical in the body’s conversion of food into energy (ATP). It is also a unique antioxidant, being both water- and fat-soluble.

 

HOW TO USE THE NUTRIENT INFORMATION

In the SupraPaks ingredients page, each nutraceutical is linked to a separate page that contains detailed information about it, divided into seven sections. Where possible, the ingredient is listed by its common or layperson name, with its more scientific name below it, in parentheses. A nutraceutical can be a vitamin, mineral, fatty acid or other type of fat, amino acid, coenzyme, other food component, herb, or an extracted ingredient from an herb.

  • Description/Function: describes each supplement in terms of its functions in the body, and in the case of herbs, native habitat, historical use, and active ingredients.
  • DRI (RDA or AI for Adults): applies to most vitamins and minerals. If there is an officially recommended amount, it is listed here, sometimes broken down by gender or age.
  • Major Sources: lists good sources, food or otherwise. Sometimes the only source of the nutraceutical is as a supplement.
  • Maintenance/Therapeutic Range: provides amounts that most people can take on a regular basis (lower range), or for short periods of time to treat an ailment (higher range). Herbal potencies usually list the amounts based on standardized extracts.
  • Possible Therapeutic Applications: lists alphabetically the health conditions that may be helped by taking the nutraceutical.
  • Comments: contains miscellaneous notes.
  • Cautions: contains possible concerns with the supplement’s usage based on health problems or medication conflicts. 

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Copyright © 2003 SupraHealth, Inc.
Last modified: 11/27/09