DESCRIPTION/FUNCTION

• Inositol is often classified as a B-vitamin. As phosphatidylinositol, it is present in cell membranes. Functions include the mediation of cellular responses to external stimuli, nerve transmissions, and regulation of enzyme activity. It also exerts lipotropic activity (fat metabolism in the liver).

DRI (RDA or AI for Adults)

• None. Classified as vitamin-like, but the body can manufacture it.

MAJOR SOURCES

• Organ meats (liver, heart), whole grains, vegetables, nuts, legumes.

MAINTENANCE/THERAPEUTIC RANGE

• 100 mg to 10,000 mg.

POSSIBLE THERAPEUTIC APPLICATIONS

• Anxiety
• Depression
• Obsessive-compulsive disorder (OCD)
• Panic disorder

COMMENTS

• Inositol exerts its psychological actions by increasing GABA levels (gamma aminobutyric acid). GABA is an inhibitory neurotransmitter. Inositol may also have antioxidant properties.

CAUTIONS

• None known, although large doses can have a laxative effect.