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Omega-6 Fatty Acid
- GLA is a derivative of the essential fatty acid, linoleic acid. Essential
fatty acids (EFAs) are precursors of the hormone-like eicosanoids
(prostaglandins, thromboxanes, leukotrienes) that participate in the regulation
of blood pressure, heart rate, vascular dilation, blood clotting, lipolysis,
immune response, and the central nervous system.
DRI (RDA or AI for Adults)
- As linoleic acid (precursor to GLA):
- Males: 19-50 (17 g); 51 and older (14 g).
- Females: 19-50 (12 g); 51 and older (11 g).
- Pregnancy/Lactation: 13 g.
- Black currant seed oil, borage seed oil, evening primrose oil.
POSSIBLE THERAPEUTIC APPLICATIONS
- Cancer (breast; when taken with tamoxifen)
- Coronary heart disease
- Fibrocystic breasts
- High blood pressure
- Premenstrual syndrome
- Rheumatoid arthritis
- Most research has been done on borage and primrose oils. The three primary
sources of GLA have varying concentrations of it: evening primrose oil (9-10%),
black current seed oil (12-14%), borage seed oil (20-24%). Taking GLA is not
likely to increase arachidonic acid (AA) levels, since most GLA from supplements
is converted to dihomo-gamma linolenic acid (DGLA), and then to prostaglandin E1
(PGE1), a beneficial prostaglandin. DGLA actually competes with AA, reducing
- Consult with your health practitioner if you are taking blood thinning drugs or
phenothiazines (GLA reduces seizure threshold).