DESCRIPTION/FUNCTION

• Folic acid is classified as a member of the B-vitamins. It appears to be essential for biosynthesis of nucleic acids; essential for normal maturation of red blood cells; functions as the coenzyme, tetrahydrofolic acid; used in one-carbon transfer reactions.

DRI (RDA or AI for Adults)

• Adults: 400 mcg.
• Pregnancy: 600 mcg.
• Lactation: 500 mcg. (Prevents some birth defects.)

MAJOR SOURCES

• Chicken liver, turkey liver, brewers yeast, veal liver, beef liver, lentils, okra, black beans, kidney beans, spinach, pasta, beef kidney, peanuts, collard greens, asparagus, navy beans, sunflower kernels, orange juice.
• Also synthesized by intestinal bacteria.

MAINTENANCE/THERAPEUTIC RANGE

• 200 mcg to 1,000 mcg. (At high doses, balance with extra vitamin B12.)

POSSIBLE THERAPEUTIC APPLICATIONS

• Cancer (breast, cervical, colorectal, pancreatic)
• Coronary heart disease
• Depression
• High homocysteine
• Infertility (male)
• Memory loss
• Ulcerative colitis

COMMENTS

• Folic acid may work with vitamins B6 and B12 in reducing homocysteine, a risk factor for heart disease. When taken during pregnancy, it reduces neural tube birth defects.

CAUTIONS

• Consult with your health practitioner if taking prescription drugs. There can be a variety of interactions between folic acid and many medications.